Nowadays chronic blepharitis that does not
respond to conventional treatment is associated with
increasing number of Demodex at eyelid. In human
eye, there are two species of mites which are
Demodex folliculorum and Demodex brevis. Due to
their habitat of these 2 species are different which
cause different kind of anterior and posterior
blepharitis, respectively. Ocular symptoms of
Demodex blepharitis are overlap to the other ocular
surface disease but symptoms may worsen than the
others. This reason may be the cause of delayed
diagnosis and ineffective management of Demodex
blepharitis. Pathognomonic sign of this disease is the
cylindrical dandruff around lash follicle. There are
many methods for confirm diagnosis which the most
popular method is lash sampling and exam under
microscope. Mode of common treatments presently,
there are many commercial eyelid cleansers that
contained tea tree oil in various concentration in the
market or oral ivermectin but all of these cannot get
rid of Demodex mite after 4 weeks of treatment. So
Demodex blepharitis is the chronic disease that challenges
both diagnosis and proper treatment for the
quality of chronic blepharitis patients in the future
Keywords
Demodex, blepharitis, ocular surface disease, cylindrical dandruff, tea tree oil