SRINAGARIND MEDICAL JOURNALVolume 35, No. 03, Month MAY, Year 2020, Pages 346 - 352
Non-aids defining illness and mortality in hiv patients
Duangjai Duangrithi, Titiwut Bhuddhataweekul, Khuntikun Polsracoo
Abstract Download PDFHIV is the virus destroying body immune system
especially, white blood cell named CD-4 cell. This
cell can protect the body from many infectious
diseases. Early antiretroviral therapy (ART) and
continuing will make people living with HIV (PLWHIV)
healthy, improve quality of life and prolong life.
Thailand national guideline on HIV/AIDS treatment
and prevention 2017 recommended the first line ART;
2 nucleoside reverse transcriptase inhibitors plus 1
non-nucleoside reverse transcriptase inhibitors. It was
called highly active ART (HAART) leading to a long life.
However, antiretroviral drugs (ARV) are associated with
lipid profile, insulin resistance and lipodystrophy
resulting in high risk of non-AIDs illness such as
cardiovascular disease and metabolic syndrome.
Although immune response has been improved after
ART but the system has not fully recovered. Therefore,
the risk of cancer and mortality rate of non-AIDs illness
is still increasing. According to privilege for PLWHIV
and AIDS by national health security, laboratory and
special investigations did not cover all non-AIDs illness.
Then, screening and diagnosis could not be performed
and accessing to prophylaxis and treatment will be
delayed. Reconsideration of their privilege will improve
patient care and promote quality of life and prolong
HIV, antiretroviral therapy, non-AIDs illness cardiovascular disease, metabolic syndrome