SRINAGARIND MEDICAL JOURNAL

Volume 36, No. 02, Month MARCH, Year 2021, Pages 222 - 228

Association between lesions of cancer and survival of colorectal cancer (crc) patients after diagnosis at maharat nakhon ratchasima hospital, nakhon ratchasima province

Kanokphan Phansranoi, Supot Kamsa-ard, Nut Boonnithi, Nintita Sripaiboonkij Thokanit, Naowarat Maneenin

Abstract Download PDF

were conversely in survival rate of the sides of colorectal cancer (CRC). Differences in the survival rate for CRC have been observed among the left-sided and right-sided tumors, with further regional variation. There was inconsistency in survival rate varies by regions. The objective of this study was to compare the survival rate between left and right-sided tumors after diagnosis of CRC patients at Maharat Nakhon Ratchasima hospital, Nakhon Ratchasima province. Methods: Data (2,096 cases) were collected from the Maharat Nakhon Ratchasima hospital-based cancer registry (2014-2018) in Nakhon Ratchasima province. The survival rate was estimated using the Kaplan- Meier method. Between group compassions were made using the Log rank test. We reported the median survival time and 95% confidence interval.Result: Of 2,096 CRC patients, 1,209 died during the study period, corresponding to a case-fatality rate of 31.4 per 100 person-years (95%CI: 29.6-33.1). The median survival time was 1.95 years. (95%CI: 1.77-2.12). The overall survival rates at 1, 3, and 5 years were 66.6% (95%CI: 64.5-68.5), 39.3% (95%CI; 37.0-41.5), and 30.3% (95%CI; 27.7-32.8), respectively. The survival rate between the left and right-sided tumors was not significantly different (Log rank test = 0.59, p=0.444). Conclusion: The survival rate between right- and left-sided CRC lesions was not significantly different. The 5-year survival rate is poor; consequently, primary prevention is crucial and screening for early detection is necessary to improve survival rate. Further research should focus on the factors affecting survival of CRC.

Keywords

Colorectal cancer; Cancer lesion; Survival rate; Cancer registry

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