From the end of December 2019, Corona Virus Disease – 19 (COVID – 19) is the
fear of people throughout the world. The causal organism behind COVID – 19 is SARS – CoV
– 2 (Severe acute respiratory syndrome corona virus). This virus creates respiratory problems in
human beings. WHO declared COVID – 19 as a pandemic disease because of its severe
infection development capability. Like many other enveloped viruses, SARS – CoV – 2 carries
glycoproteins on their surface. These glycoproteins are mainly responsible for the infection
processes. They have involved in the receptor binding phenomenon. These glycoproteins are
also involved in retrovirus particle and host cell membrane fusion. So, they may be potential
targets for the development of novel corona viral therapies. Carbohydrate - Binding Agents
(commonly called CBA) have antiviral activity towards the Corona virus. Plant lectins have
anti-viral activities against Coronavirus species. In this review, we discussed thoroughly about
the role of plant lectins in destroying Coronavirus infection. Plant lectins may be the potential
source of herbal drugs of COVID – 19.