The antibacterial and anti-tyrosinase activities of methanolic extracts from fresh and
fallen leaves of Tectona grandis (Teak) was studied. Fresh and fallen of teak leaves were
collected from Thongphaphum and Phitsanulok silviculture research station. Antibacterial
activity was determined by disc diffusion method with concentration at 500 μg/disc. Fresh and
fallen of teak leaves extracts showed a good activity against Staphylococcus aureus and
Staphylococcus epidermidis. In the other hand, fresh teak leaves inhibited growth of
Propionibacterium acnes better than fallen teak leaves. The anti-tyrosinase activity was
determined by Dopachrome method with concentration at 1500 μg/ml, inhibitory power of
tyrosinase enzyme from fresh and fallen leaves extracts value were detected in the percentage
between 35.45%-73.65%.