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NARESUAN UNIVERSITY JOURNAL OF SCIENCE AND TECHNOLOGY


Volume 27, No. 03, Month JULY, Year 2019, Pages 35 - 42


Antioxidant activities and electrochemical behaviors of xanthones from cratoxylum cochinchinense and cratoxylum formasum

Benjamat Chailap, Thanesuan Nuanyai


Abstract Download PDF

Seven xanthones; dulcisxanthone B (1), ß-mangostin (2), 1,3,7-trihydroxy-2,4-di-(3-methylbut-2-eyl)-xanthone (3), cudratricusxanthone E (4), cochinchinone A (5), 2-geranyl-1,3,7-trihydroxy-4-(3,3-dimethylallyl)-xanthone (6), and cochinchinone B (7) were isolated from twigs of Cratoxylum cochinchinense and Cratoxylum formasum. The structures of all isolated compounds were elucidated by spectroscopic methods (1H, 13C, 1H-1H COSY, 1H-13C HSQC, and 1H-13C HMBC) and compared with previous literatures. All compounds were evaluated in vitro for antioxidant activity using DPPH assay. Their electrochemical behaviors were investigated by cyclic voltammetry. The results derived from two techniques were consistent. Compounds 1, 2, 4 and 7 exhibited strong antioxidant activities. Considering the structure-activity relationship, the hydroxy group at C-6 played an important role to antioxidant power.


Keywords

Xanthone, Cratoxylum cochinchinense, Cratoxylum formasum, Antioxidant, Electrochemical



NARESUAN UNIVERSITY JOURNAL OF SCIENCE AND TECHNOLOGY


Published by : Naresuan University
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